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Gonadorelin

FDA-Approved• Prescribable
peptideSubcutaneous injection

A lab-made version of the hormone your brain uses to tell your pituitary gland to release LH and FSH (the hormones that drive testosterone production and fertility). Commonly used to keep the testes functioning during testosterone replacement therapy.

Dosing

100-200 mcg subq twice a week. Often used alongside TRT.

Benefit Profile

🧬 Fertility & Hormones
9/10
💪 Muscle Growth
3/10

Pricing

VendorVariantPrice
Skye Peptides2mg$24.99
Swiss Chems
FDA warning letter received late 2024
2mg$24.95
Amino Asylum
Reported federal raid in 2025
2mg$19.99BEST
Peptide Sciences
Announced voluntary shutdown
2mg$29.00

Published Research

20 studies indexed(2000–2025)2 clinical trials15 reviews

Effect of 200 µg of gonadorelin at the first gonadotropin-releasing hormone of the Resynch-25 on ovarian dynamics and fertility in lactating Holstein cows.

Leão IMR, El Azzi MS, et al.·J Dairy Sci·2024
Clinical Trial

Effect of different gonadorelin (GnRH) products used for the first or resynchronized timed artificial insemination on pregnancy rates in postpartum dairy cows.

Poock SE, Lamberson WR, Lucy MC·Theriogenology·2015
Clinical Trial

Effects of GnRH agonists and antagonists on cardiovascular and metabolic systems in adults: Mechanistic pathways and risk management.

Etezadi A, Marashi SM, et al.·Biomed Pharmacother·2025
Review

Advances and perspectives in the analytical technology for small peptide hormones analysis: A glimpse to gonadorelin.

Torrini F, Scarano S, et al.·J Pharm Biomed Anal·2023
Review

Hypothalamic mechanisms of obesity-associated disturbance of hypothalamic-pituitary-ovarian axis.

Chen X, Xiao Z, et al.·Trends Endocrinol Metab·2022
Review

Role of Gonadotropin-Releasing Hormone (GnRH) in Ovarian Cancer.

Gründker C, Emons G·Cells·2021
Review

The Role of Gonadotropin-Releasing Hormone (GnRH) in Endometrial Cancer.

Emons G, Gründker C·Cells·2021
Review

Gonadotropin-Releasing Hormone and GnRH Receptor: Structure, Function and Drug Development.

Tzoupis H, Nteli A, et al.·Curr Med Chem·2020
Review

Effect of Inflammation on Female Gonadotropin-Releasing Hormone (GnRH) Neurons: Mechanisms and Consequences.

Barabás K, Szabó-Meleg E, Ábrahám IM·Int J Mol Sci·2020
Review

Investigational and experimental GnRH analogs and associated neurotransmitters.

Blumenfeld Z·Expert Opin Investig Drugs·2017
Review
Showing 10 of 20 studies. Search PubMed for the complete list.

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