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IGF-1 LR3

Research Use Only
peptideSubcutaneous injection

A modified version of IGF-1 (a powerful growth signal) that lasts longer in your body. What makes it special is it can actually create new muscle cells (not just make existing ones bigger), making it one of the most potent muscle-building peptides out there.

Dosing

20-50 mcg subq daily, after a workout or split between morning and evening. Cycle for 4-6 weeks max.

Benefit Profile

💪 Muscle Growth
10/10
🩹 Injury Healing
5/10
🔥 Fat Loss
4/10

Pricing

VendorVariantPrice
Swiss Chems
FDA warning letter received late 2024
1mg$74.95
Amino Asylum
Reported federal raid in 2025
1mg$59.99BEST
Peptide Sciences
Announced voluntary shutdown
1mg$89.00

Published Research

20 studies indexed(1999–2025)1 review

The role of insulin-like growth factors in small intestinal cell growth and development.

MacDonald RS·Horm Metab Res·1999
Review

IGF-1 LR3 does not promote growth in late-gestation growth-restricted fetal sheep.

White A, Stremming J, et al.·Am J Physiol Endocrinol Metab·2025
Research Article

Revolutionary decellularized Alstroemeria stem-based nerve conduit integrated with GelMA and controlled IGF-1 LR3 release for enhanced rat sciatic nerve regeneration.

Yavuz E, Sağır MS, et al.·Int J Biol Macromol·2025
Research Article

Intranasal long R3 insulin-like growth factor-1 treatment promotes amyloid plaque remodeling in cerebral cortex but fails to preserve cognitive function in male 5XFAD mice.

Engel MG, Narayan S, et al.·J Alzheimers Dis·2025
Research Article

Chromatographic-mass spectrometric analysis of peptidic analytes (2-10 kDa) in doping control urine samples.

Thomas A, Walpurgis K, Thevis M·J Mass Spectrom·2024
Research Article

Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris.

Lu Z, Liu N, et al.·Appl Microbiol Biotechnol·2023
Research Article

Attenuated glucose-stimulated insulin secretion during an acute IGF-1 LR3 infusion into fetal sheep does not persist in isolated islets.

White A, Stremming J, et al.·J Dev Orig Health Dis·2023
Research Article

Insulin-Like Growth Factor1 Preserves Gastric Pacemaker Cells and Motor Function in Aging via ERK1/2 Activation.

Truong Thuy Nguyen V, Taheri N, et al.·Cell Mol Gastroenterol Hepatol·2023
Research Article

Sheep recombinant IGF-1 promotes organ-specific growth in fetal sheep.

Stremming J, White A, et al.·Front Physiol·2022
Research Article

N-Linked Glycosylation in Chinese Hamster Ovary Cells Is Critical for Insulin-like Growth Factor 1 Signaling.

Salvi R, Kumar C, et al.·Int J Mol Sci·2022
Research Article
Showing 10 of 20 studies. Search PubMed for the complete list.