A brain-boosting peptide derived from a natural nerve-protecting protein (PEDF). It strengthens memory formation and sharpens cognitive performance through a unique mechanism that's different from other popular nootropics like Semax.
Dosing
200-500 mcg as a nasal spray or subq daily. Cycle 4 weeks on, then take a break.
Benefit Profile
Published Research
Functional Roles of Pigment Epithelium-Derived Factor in Retinal Degenerative and Vascular Disorders: A Scoping Review.
A PEDF-Derived Short Peptide Prevents Sodium Iodate-Induced Retinal Degeneration in Rats by Activating the SLC7A11/GSH/GPX4 Pathway in the RPE Cells.
Proteomic profiling of adipose-derived mesenchymal stromal cell response to novel compounds targeting the Laminin Receptor - PEDF interaction.
PEDF-derived peptide protects against Amyloid-β toxicity in vitro and prevents retinal dysfunction in rats.
Corrigendum to "PEDF and PEDF-derived peptide 44mer inhibit oxygen-glucose deprivation-induced oxidative stress through upregulating PPARγ via PEDF-R in H9c2 cells" [Biochem. Biophys. Res. Commun. 473 (3) (2016) 482-488].
A short peptide derived from pigment epithelial-derived factor exhibits an angioinhibitory effect.
The Therapeutic Effects of a PEDF-Derived Short Peptide on Murine Experimental Dry Eye Involves Suppression of MMP-9 and Inflammation.
Exploration of novel anti-angiogenic PEDF-derived peptides with improved activitives by inhibiting proliferation, suppressing migration, and inducing 67LR internalization.
Inhibition of retinal neovascularization by a PEDF-derived nonapeptide in newborn mice subjected to oxygen-induced ischemic retinopathy.
PEDF-derived peptide promotes tendon regeneration through its mitogenic effect on tendon stem/progenitor cells.